Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJMBR (3) Autor Gomes,F.C.A. (3) Moura Neto,V. (2) Alvarez,A. (1) Garcia-Abreu,J. (1) Maccioni,R.B. (1) Martinez,R. (1) Moura-Neto,V. (1) Paulin,D. (1) Ramírez,G. (1) Spohr,T.C.L.S. (1) Mais... Palavra-chave Astrocyte (2) CNS (1) Extracellular matrix (1) GFAP (1) GFAP gene (1) Growth factors (1) Intermediate filaments (1) Nervous system (1) Neuron (1) Neuron-glia interaction (1) Neuronal morphogenesis (1) Regulatory patterns (1) Tau functions (1) Trophic factors (1) Vimentin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2001 (1) 1999 (2) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Cross-talk between neurons and glia: highlights on soluble factors BJMBR Gomes,F.C.A.; Spohr,T.C.L.S.; Martinez,R.; Moura Neto,V.. The development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership. Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuron-glia interaction; Trophic factors; Astrocyte; Neuron; Nervous system. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008 Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation BJMBR Gomes,F.C.A.; Paulin,D.; Moura Neto,V.. Intermediate filament (IF) proteins constitute an extremely large multigene family of developmentally and tissue-regulated cytoskeleton proteins abundant in most vertebrate cell types. Astrocyte precursors of the CNS usually express vimentin as the major IF. Astrocyte maturation is followed by a switch between vimentin and glial fibrillary acidic protein (GFAP) expression, with the latter being recognized as an astrocyte maturation marker. Levels of GFAP are regulated under developmental and pathological conditions. Upregulation of GFAP expression is one of the main characteristics of the astrocytic reaction commonly observed after CNS lesion. In this way, studies on GFAP regulation have been shown to be useful to understand not only brain physiology but... Tipo: Info:eu-repo/semantics/article Palavras-chave: CNS; Astrocyte; Growth factors; Intermediate filaments; GFAP; Vimentin; GFAP gene. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500016 Regulatory roles of microtubule-associated proteins in neuronal morphogenesis. Involvement of the extracellular matrix BJMBR Ramírez,G.; Alvarez,A.; Garcia-Abreu,J.; Gomes,F.C.A.; Moura-Neto,V.; Maccioni,R.B.. As a result of recent investigations, the cytoskeleton can be viewed as a cytoplasmic system of interconnected filaments with three major integrative levels: self-assembling macromolecules, filamentous polymers, e.g., microtubules, intermediate filaments and actin filaments, and supramolecular structures formed by bundles of these filaments or networks resulting from cross-bridges between these major cytoskeletal polymers. The organization of this biological structure appears to be sensitive to fine spatially and temporally dependent regulatory signals. In differentiating neurons, regulation of cytoskeleton organization is particularly relevant, and the microtubule-associated protein (MAP) tau appears to play roles in the extension of large neuritic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Extracellular matrix; Tau functions; Regulatory patterns; Neuronal morphogenesis. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500015 Registros recuperados: 3 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco